The regulation of APC2 and Arm is altered in akt embryos. (A) Immunoprecipiation of Arm from 0–3-h wild-type and akt1⁰⁴²²⁶ embryo extracts. Pros-35 is shown as a control. T, total extract; S, supernatant; P, pellet. (B) The mobility of APC2 in akt1⁰⁴²²⁶ embryos can be altered by treatment with λ phosphatase. (C) Wild-type and akt1⁰⁴²²⁶ embryos fixed and stained to visualize DNA and APC2. In akt embryos, APC2 fails to localize. Bar, 10 μm.