Figure 3.
Dimeric structures of ElbB, HchA, and YhbO weaken cPGA binding. (A) Overlaid image of the DJ-1 or YajL molecular model complexed with cPGA. Magnified view shows the cPGA-binding site (orange) with the surface structure of DJ-1 (gray) and YajL (blue). (B) Molecular model of the cPGA-binding site in ElbB (blue). The helix-forming residues of ElbB that interfere with cPGA binding are highlighted in red. (C) Molecular model of the HchA–cPGA complex with a magnified view. (D) Overlaid image of DJ-1 or YhbO complexed with cPGA. Magnified view shows the surface structure of YhbO in proximity to the cPGA-binding site.