The C-terminal region of MpH that is altered by the mpH-1 mutation is conserved in other ciliates. A multiple sequence alignment of TTHERM_00564170/MpH with its orthologs in Ichthyophthirius multifiliis (IMG5_005100), P. tetraurelia (GSPATT00023390001), and S. coeruleus (SteCoe_10711). The C-terminal region, altered and truncated in the mpH-1 mutant, is marked with the red line above the alignment.