Type A receptor–like particles are more closely associated with nanoblocks than type B particles. (A) Examples show distribution of docked or tethered or partially fused vesicles, type A/B particles, undefined particles, and PSD nanoblocks projected onto the postsynaptic membrane in synaptosomes. Scale bars: 50 nm. (B) A schematic showing the distance d1 between receptor-like particle and the PSD nanoblock centroid and distance D between the nanoblock centroid and the farthest edge. (C and D) Distribution of the normalized distance d1/D between type A particles and nanoblocks and between type B particles and nanoblocks. Two-sample Kolmogorov–Smirnov test, n = 207 for type A particles and n = 93 for type B particles, D = 0.2551, P = 3.54 × 10−4. (E and F) Distribution of the normalized distance d1/D between type A and B particles and nanoblocks and between undefined particles and nanoblocks. Two-sample Kolmogorov–Smirnov test, n = 300 for type A and B particles and n = 457 for undefined particles, D = 0.13055, P = 3.53 × 10−3.
