Drs2, Tlg2, and Snc2 label the same compartment in starvation—modified TGN. Cells co-expressing GFP-Tlg2 with Drs2-3xmCherry or mCherry-Snc2 were visualized by spinning-disk confocal microscopy in the indicated conditions. In both combinations, average Pearson’s coefficient increased from ∼0.3 in the growth to ∼0.7 in the starvation condition (n = 25–40 cells). Scale bar = 2 μm.