Figure S7.
YAP reduction in TEM4-depleted cell lines. (A) HeLa cells were treated with an increasing dose of the YAP inhibitor verteporfin for 24 h. Lysates were generated and probed with the indicated antibodies by western blotting. * TAZ band. (B) Quantification of western blots shown in Fig. 8 A. (C) Correlation of ARHGEF17 and YAP1 gene expression. Data generated via Depmap portal. (D) Correlation of TEM4 and YAP protein levels from publicly accessible proteomics datasets. Data generated via Depmap portal. (E) TEM4-21 and TEM4-22 cells were left uninduced or were induced for the indicated time points and lysates were probed as indicated. (F) Control, TEM4-21, and TEM4-22 cells were treated with 1 µM verteporfin for 24 h as indicated before immunoblotting for YAP and tubulin. Source data are available for this figure: SourceData FS7. Refer to the image caption for details.

YAP reduction in TEM4-depleted cell lines. (A) HeLa cells were treated with an increasing dose of the YAP inhibitor verteporfin for 24 h. Lysates were generated and probed with the indicated antibodies by western blotting. * TAZ band. (B) Quantification of western blots shown in Fig. 8 A. (C) Correlation of ARHGEF17 and YAP1 gene expression. Data generated via Depmap portal. (D) Correlation of TEM4 and YAP protein levels from publicly accessible proteomics datasets. Data generated via Depmap portal. (E) TEM4-21 and TEM4-22 cells were left uninduced or were induced for the indicated time points and lysates were probed as indicated. (F) Control, TEM4-21, and TEM4-22 cells were treated with 1 µM verteporfin for 24 h as indicated before immunoblotting for YAP and tubulin. Source data are available for this figure: SourceData FS7.

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