DICE improvement during post-processing. DICE development at different post-processing steps of predicted masks (different colors correspond to different steps). Each dot corresponds to a tomogram. (A–C) synaptosomal train set (B) synaptosomal within-distribution test set (C) neuronal out-of-distribution test set. Boxplot: Box edges show 25th and 75th percentiles, the middle line is the median. Whiskers extend to the last points within 1.5 times the interquartile range. Points beyond are outliers.