Figure S2.
Altered proportion of cells in cell cycle phases in Eml1 mutant conditions. (A) Examples of PCNA and Ki67 labeling patterns (cropped nuclei) for different cell cycle phases, punctate Ki67, or PCNA are indicated with a red arrow. (B) Representative images for PCNA and Ki67 labeling at E12.5 in WT and Eml1 cKO cells in the VZ. (C) Quantification for the percentage of proliferating cells in S, G1, or G2/M phases of the cell cycle expressed as mean ± SEM. n = 6 individuals per genotype at E12.5. (D and E) Similar analyses were performed at E15.5, with n = 5 individuals per genotype. Test and significance: Two-way ANOVA, Sidak’s multiple comparison (E12.5), Tukey’s post-test at (E15.5). Data passed normality test. P value <0.05 *, <0.001 *** Scale bar (equivalent for WT and cKO): 30 µm.

Altered proportion of cells in cell cycle phases in Eml1 mutant conditions. (A) Examples of PCNA and Ki67 labeling patterns (cropped nuclei) for different cell cycle phases, punctate Ki67, or PCNA are indicated with a red arrow. (B) Representative images for PCNA and Ki67 labeling at E12.5 in WT and Eml1 cKO cells in the VZ. (C) Quantification for the percentage of proliferating cells in S, G1, or G2/M phases of the cell cycle expressed as mean ± SEM. n = 6 individuals per genotype at E12.5. (D and E) Similar analyses were performed at E15.5, with n = 5 individuals per genotype. Test and significance: Two-way ANOVA, Sidak’s multiple comparison (E12.5), Tukey’s post-test at (E15.5). Data passed normality test. P value <0.05 *, <0.001 *** Scale bar (equivalent for WT and cKO): 30 µm.

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