Figure S2.

Related to Fig. 2 : Macrophage phagocytosis and trogocytosis in 3D spheroids. (A) The top row shows an Her2 CAR GFP (green) macrophage phagocytosing an SKOV3 (mCherry-CAAX) cell in a 3D spheroid. The images are stills from Video 5. The dashed line and the asterisk denote the cell that will be phagocytosed. Scale bar is 20 µm. The bottom row shows still images of Her2 CAR GFP (green) macrophages that trogocytosed, as evidenced by the small bites of SKOV3 (mCherry-CAAX) cells within the macrophage. (B) Plot shows the fold change in diameter of each individual spheroids from the Her2 CAR treatment condition over the 10 days time course.

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