Secretome analysis in mutant cells. (A) Log₂ sum of raw peptide abundance in each proteomics replicate from the secretome analysis shown in Fig. 5. (B) Principal component analysis of the secretome data sets represented in Fig. 5. (C) Heat map comparing protein abundance changes between the two different golgin KOs in the secretome experiment. Red and blue indicate increased and decreased abundance, respectively, and intensity of color is determined by the average log fold change across mutants compared with WT.