Model for NEKL-4 function in relation to cilia, mitochondria, and CCPP-1. NEKL-4 functions in the ciliated neurons to reduce mitochondrial oxidative stress and destabilize ciliary B-tubules through the action of ciliary kinesins such as KLP-13. This ciliary function opposes the B-tubule stabilizing action of CCPP-1 through a pathway distinct from glutamylation regulation. CCPP-1 also promotes dendritic transport in the ciliated neurons, specifically the transport of mitochondria. Created with https://BioRender.com (license BE26DR2HV3).