Figure 9.

Predicted structures of the Leep2 complex. (A) Ribbon representation of the predicted structure of the Leep2 complex in two different views. (B) Ribbon representation of the predicted structure of the Leep2 complex. The T5 fragments and GAP domains in Leep2A and Leep2B are highlighted. (C) Mapping of pLDDT score per residue onto the predicted Leep2 complex structure. pLDDT stands for predicted local distance difference test, which indicates the confidence level of the prediction. (D) Ribbon representation of the predicted heterodimeric structure of Leep2A, Leep2B, and RasD. Comparable structures were predicted with RasG or RasB. (E) Surface representation of the predicted structure in D, except that the GAP domain in Leep2A and Leep2B is colored in cyan and pink, respectively. (F) Left: Ribbon representation of the predicted structure of the GAP domain of Leep2A and RasD. Right: Mapping of pLDDT score per residue onto the predicted complex structure of Leep2A GAP domain and RasD. (G) Left: Ribbon representation of the predicted structure of the GAP domain of Leep2B and RasD. Right: Mapping of pLDDT score per residue onto the predicted complex structure of Leep2B GAP domain and RasD.

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