SWIN A disrupts actin rings in progenitor-derived neuronal cells. (a) STED image of DIV6 progenitor-derived neuronal cells treated with 1% (vol/vol) DMSO for 30 min and subsequently fixed and stained for actin using phalloidin. (b) Like (a), but neuronal cells were treated with 1 µM SWIN A for 30 min. (c) Zoom-in of box in (a). Actin rings are ubiquitous in control cells. (d) Zoom-in of box in (b). Actin rings are disrupted in SWIN A treated cells. (e) Autocorrelation function (ACF) along dotted line in (c) shows periodicity of actin rings ∼200 nm. (f) Like (e), but for dotted line in (d). Even though actin rings are disrupted in SWIN A treated cells, they remain partially intact. Scale bars are 1 µm.