Identification of the hydrophobic cavity of potential LTPs. (A–F) Spatial density maps (A–F) of (A) Svf1, (B) SNX25, (C) Nvj3, (D) Mdm31, (E) AsmA, and (F) Lec1. The two lipocalin domains of Svf1 are shown in blue and violet. The PXA and PXC domains of SNX25 and Nvj3 are displayed in red and orange, respectively. The PXYn, PX, and PXYc domains of Lec1 are displayed in green, blue, and orange, respectively (notation and colors as in Paul et al., 2022). Averaged lipid tail densities are shown in green. (G) Lipid tail solvation for the six potential LTPs; only the replicas with lipid binding were considered for the analysis.