Lipid binding to Takeout and JHBP proteins. (A) Time trace of minimum distance values between the lipids and the Takeout and JHBP proteins (red) along with the lipid tail solvation (blue). Both plots have been block-averaged every 10 frames. (B) Lipid tail solvation in the last 100 ns of the trajectories, mean value for positive LTP is shown as a dotted line.