Figure 6.
RRBP1 knockdown reduces riboMERCS independent of Gp78. (A) Representative EM images of HT-1080 and HT-1080 Gp78 KO cells treated with either siControl or siRRBP1. Images highlight the presence of riboMERCS in both HT-1080 WT and Gp78 KO cells, which are almost completely lost upon RRBP1 knockdown. (B) Quantification of the number of riboMERCs per mitochondria and the ratio of riboMERC length to mitochondrial perimeter for the conditions in A. (C) Quantification of the MERC width for both riboMERCs and smooth MERCs for the conditions in A. n = 31 images from two independent biological replicates; **P < 0.01; ***P < 0.001; ****P < 0.0001; unpaired t test. Bar = 200 nm.

RRBP1 knockdown reduces riboMERCS independent of Gp78. (A) Representative EM images of HT-1080 and HT-1080 Gp78 KO cells treated with either siControl or siRRBP1. Images highlight the presence of riboMERCS in both HT-1080 WT and Gp78 KO cells, which are almost completely lost upon RRBP1 knockdown. (B) Quantification of the number of riboMERCs per mitochondria and the ratio of riboMERC length to mitochondrial perimeter for the conditions in A. (C) Quantification of the MERC width for both riboMERCs and smooth MERCs for the conditions in A. n = 31 images from two independent biological replicates; **P < 0.01; ***P < 0.001; ****P < 0.0001; unpaired t test. Bar = 200 nm.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal