Figure 3.

Elasticity of SAC. (A) Snapshots taken at the initial configuration (left), at maximum extension with F ∼ 4 pN (center), and after full retraction (right). (B) Changes in chromosome extension over time as the chromosome is first extended (for ∼5 min from its natural length [dotted horizontal line]) by different pulling forces F, before the pulling force is turned off and the chromosome relaxes. Loops have a fixed size Lloop = 80 kbp and soft potential A = 10 kBT. Typical pulling force values are indicated in the legend. Each curve refers to a single simulation run.

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