Overexpression of a constitutively active TAZ mutant affects REV-ERBα expression. (A) Violin plots representing the distribution of the single-cell RevVNP circadian power fractions of control and TAZ-overexpressing cells carrying a 4SA dominant positive mutation; n = 3,097 and 2,359, respectively, from five independent experiments. Two-sided Wilcoxon rank sum test; **** indicates P value <0.0001. (B) Confocal microscopy images of control and 4SA-TAZ cells immunostained against REV-ERBα. All images are displayed under the same brightness and contrast settings. Scale bar, 20 µm. (C) Violin plots representing the single-cell levels of nuclear REV-ERBα. n = 134 for the control and 123 for 4SA-TAZ, from one representative of three independent experiments. Two-sided Wilcoxon rank sum test; **** indicates P value <0.0001.