Figure S11. Rtnl1 loss decreases ER Ca 2... | Rockefeller University Press

Figure S11.

Rtnl1 loss decreases ER Ca2+handling in Type Is and Ib boutons. (Extended data from Figs. 6 and 7.) (A) Impact of Rtnl1 loss-of-function on evoked ER Ca2+ in Is boutons. Plots show all single time traces and mean ± SEM time traces in both genotypes for the five stimulation frequencies tested. Sample size (larvae) is indicated within the plot for each genotype. Genotypes are Is-GAL4, UAS-ER-GCaMP6-210/UAS-tdTom::Sec61β, in either a WT or Rtnl118 background. (B) Impact of Rtnl1 loss of function on evoked ER Ca2+ in Ib boutons, plotted as in A. Genotypes are Ib-GAL4, UAS-ER-GCaMP6-210/UAS-tdTom::Sec61β, in either a WT or Rtnl118 background.

Rtnl1 loss decreases ER Ca ²⁺ handling in Type Is and Ib boutons. (Extended data from Figs. 6 and 7.) (A) Impact of Rtnl1 loss-of-function on evoked ER Ca²⁺ in Is boutons. Plots show all single time traces and mean ± SEM time traces in both genotypes for the five stimulation frequencies tested. Sample size (larvae) is indicated within the plot for each genotype. Genotypes are Is-GAL4, UAS-ER-GCaMP6-210/UAS-tdTom::Sec61β, in either a WT or Rtnl1¹⁸ background. (B) Impact of Rtnl1 loss of function on evoked ER Ca²⁺ in Ib boutons, plotted as in A. Genotypes are Ib-GAL4, UAS-ER-GCaMP6-210/UAS-tdTom::Sec61β, in either a WT or Rtnl1¹⁸ background.