Model for clathrin coat growth. (A) Schematic of the cooperative curvature model, where clathrin lattices grow by the addition of triskelia to the edge at a constant growth rate k_on. Curvature generation is driven toward a preferred curvature, ultimately creating a spherical vesicle. (B) Distinct clathrin growth models and rolling median (window width = 82 sites) fitted to curvature over θ. (C and D) The resulting fitting parameters are then used to map the same models also over (C) surface area and (D) edge length. (n = 1,645 sites, N = 13 cells).