Figure 2.
Equilibrium binding analysis of CAS, CAS truncation mutants, and associated transport complexes for the selection of FG Nups. Equilibrium dissociation constants (KD) describe the apparent binding affinity of each CAS complex to Nup214, Nup62, Nup98, and Nup153 (N ≥ 4). Box plots denote the median, first, and third quartiles. The whiskers represent the minimum and maximum values. Mean values are indicated below the box plots. The binding range of standalone Kapβ1 (black dashed lines) and Kapα·Kapβ1 (red dashed line) to each of the FG Nups is shown for comparison. See Kapinos et al. (2017) for details. P values were obtained using an unpaired two-tailed t test.

Equilibrium binding analysis of CAS, CAS truncation mutants, and associated transport complexes for the selection of FG Nups. Equilibrium dissociation constants (KD) describe the apparent binding affinity of each CAS complex to Nup214, Nup62, Nup98, and Nup153 (N ≥ 4). Box plots denote the median, first, and third quartiles. The whiskers represent the minimum and maximum values. Mean values are indicated below the box plots. The binding range of standalone Kapβ1 (black dashed lines) and Kapα·Kapβ1 (red dashed line) to each of the FG Nups is shown for comparison. See Kapinos et al. (2017) for details. P values were obtained using an unpaired two-tailed t test.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal