Figure 8.

Dimensions of clathrin-coated pits, coated vesicles, and caveolae. (A) Violin plots of width and height for caveolae (CAV) and endocytic clathrin-coated pits (CCP) in the raw images of the structures identified by the coated pit model in cell 17 (see also Fig. S9, and Clathrin-coated pits and vesicles, Materials and methods). (B) Violin plots of the major and minor axis and eccentricity of the fitted ellipse of all pits and vesicles in the raw images of the structures identified by the coated pit model in cell 17 (see also Fig. S9, and Clathrin-coated pits and vesicles, Materials and methods). (C) The left-hand panel shows the distribution of height versus neck width for endocytic clathrin-coated pits in cell 17, identified by the coated pit model. The plot shows two clusters, which correspond to early and late coated pits, respectively, as illustrated by the schematics (see also Fig. S9, and Clathrin-coated pits and vesicles in Materials and methods). The right-hand panel shows histograms for height and major axis of the fitted ellipse for late endocytic coated pits and coated vesicles, respectively.

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