shRNA-mediated silencing of Lpd. (A) Representative confocal micrograph of RAW 264.7 macrophages stained for Lpd (red) and transfected with Lpd-shRNA (green). (B) Quantification of the mean fluorescence intensity of Lpd staining in Lpd-shRNA (n = 16) and control cells (n = 16). Unpaired t test of individual values across n = 3 independent experiments; data are means ± SEM. (C) Representative confocal micrograph of RAW 264.7 macrophages stained for Lpd (red) and transfected with Ctrl-shRNA (green). (D) Quantification of the mean fluorescence intensity of Lpd staining in Ctrl-shRNA (n = 10) and control cells (n = 10). Unpaired t test of individual values across n = 3 independent experiments; data are means ± SEM. **, P < 0.01.