Figure 6.

Glucose restriction promotes metabolic remodeling favoring peroxisome FAO. (A) Volcano plot showing log10 P value and log2 abundance changes in whole-cell abundance of proteins in 4-h AGR treatment versus 2% glucose log-phase growth. Proteins on right are increased in whole-cell abundance with 4 h AGR, and those on the left decreased in abundance. Data are average of four independent experiments. (B) Schematic of inter-organelle interactions from proteomics depicted in A. (C) Cartoon of working model for AGR-induced LCL-LD formation, and protein retargeting of various LD proteins.

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