Figure 4.
SNAP23 deficiency disrupts AJCs in RGCs.(A–L) N-cadherin (A and G), β-catenin (B and H), Par3 (C and I), ZO-1 (D and J), Crb3 (E and K), and Pals1 (F and L) stained in coronal sections of the cerebrum (A–F) or in sagittal sections of the cerebellum (G–L) at E13.5. Scale bars, 20 µm. Arrows in A and G indicate the ventricular surface. The arrowhead in G indicates the surface of the choroid plexus. Staining revealed that each marker remained at the surface of the choroid plexus in the NcKO mice because SNAP23 was not depleted in this region (see also Fig. 1 M). (M) Electron micrographs of the lateral ventricular (LV) surface of the cerebral cortex at E13.5. The electron-dense lines indicate that AJCs (arrowheads) were rarely observed in the NcKO cortex. Scale bar, 5 µm. Ctrl, control.

SNAP23 deficiency disrupts AJCs in RGCs. (A – L) N-cadherin (A and G), β-catenin (B and H), Par3 (C and I), ZO-1 (D and J), Crb3 (E and K), and Pals1 (F and L) stained in coronal sections of the cerebrum (A–F) or in sagittal sections of the cerebellum (G–L) at E13.5. Scale bars, 20 µm. Arrows in A and G indicate the ventricular surface. The arrowhead in G indicates the surface of the choroid plexus. Staining revealed that each marker remained at the surface of the choroid plexus in the NcKO mice because SNAP23 was not depleted in this region (see also Fig. 1 M). (M) Electron micrographs of the lateral ventricular (LV) surface of the cerebral cortex at E13.5. The electron-dense lines indicate that AJCs (arrowheads) were rarely observed in the NcKO cortex. Scale bar, 5 µm. Ctrl, control.

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