Validation of homology model using GREMLIN. Related to Fig. 1. (A) WebLogo representation of conserved residues on Ypq1 based on covariation analysis of 420 related eukaryotic sequences using GREMLIN. Gray boxes correspond to transmembrane helices, and black connecting lines correspond to loops. (B) Conserved residues mapped on the homology model of Ypq1.