Figure 8.

A model of furrow induction by polar relaxation. Schematic showing how bidirectional cortical flow triggered by dynein-dependent removal of myosin II from the polar cortexes leads to cleavage furrow formation. In the one-cell stage C. elegans embryo, this pathway provides a mechanism crucial for the initial induction of the cleavage furrow before the equatorial stimulation from the central spindle becomes effective.

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