Figure 2.

Characterization of polyploid mitosis in Drosophila NBs. (A) XY plot representing DNA and cell area in polyploid NBs (n = 112 NBs from 37 BL). (B) Dot plot showing the time spent in mitosis for Ctrl (n = 34 NBs from 2 BL) and polyploid (n = 60 NBs from 31 BL) NBs. (C) XY plot representing the mitotic timing and cell area (n = 60 NBs from 31 BL). (D) Schematic representation of NI calculation. (E) Dot plot of NI in Ctrl (n = 34 NBs from 2 BL) and polyploid NBs (n = 54 NBs from 28 BL). (F) XY plot of nuclei at anaphase and cell area (n = 107 NBs from 37 BL). (B and E) Statistical significance by a Mann-Whitney test. Error bars represent the mean ± SD (B) and the median ± interquartile range (E). (A, C, and F) Statistical significance of the correlation by a Spearman r test. ns, not significant; p, P value; r, correlation coefficient; Nb, number.

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