Relation between the identified binding motifs and the subunit topology of the Bim1–Cik1-Kar3 complex. Display of chemical cross-linking data from (Molodtsov et al., 2016). Each line represents an individual Lys-Lys cross-link. Cross-links to Bim1 are highlighted in red and listed on the left. Numbers in parenthesis indicate the cross-linked lysine residue. The positions of Bim1-binding motifs A, B, and C are indicated; blue lines in the protein schemes denote all available lysine residues in the primary sequence.