Model of the clathrin/TACC3 complex on a MT. Schematic model of the clathrin/TACC3 complex on a MT based on studies to date. The Aurora A–dependent phosphorylation of S558 on TACC3 is represented as a P. TACC3 is also bound to the MT polymerase ch-TOG. The CHC NTD recruits GTSE1 to inhibit the MT depolymerase MCAK. It is unknown whether PI3K-C2a and GTSE1 can interact with a single CHC on the spindle. Relative protein sizes are roughly conserved.