Figure 4.

TOPBP1-dependent phosphorylation GO analysis. (A) Functional GO network displaying grouping of GO terms enriched in TOPBP1-dependent phosphoproteins. Phosphoproteins and their corresponding GO terms were assigned functional groups after iterative merging of groups containing 50% of the same proteins. Each node in the network represents a GO term with a P value <0.05. A larger node size corresponds to more significant enrichment. Functional groups are indicated by color and represented in colored text by the most significant term in that group. Nodes with multiple colors belong to multiple groups. (B) Table displaying the 10 most highly enriched GO groups. The first term for each group represents the GO term with the highest significant enrichment. The second term for each group had the highest percentage of associated proteins for that GO group.

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