Figure 1.
The motor domain and nonconventional neck structure of NOD are required for MT binding and become enriched at MT plus ends when dimerized. (A) Schematics of the FL NOD and dimerized NOD485CC. (B) Maximum projections of two-color spinning disc confocal images showing the chromosomal localization of FL NOD overexpressed in Drosophila S2 cells. (C) Maximum projections of two-color spinning disc confocal images of Drosophila S2 cells expressing NOD motor domain (NOD324) and a NOD truncation including the motor and neck extension region (NOD485) plus and minus the dimerizing CC. NOD is shown in red; tubulin is shown in green. Bars, 10 µm.