The DCC is specifically disrupted in the absence of SPATA7. (a) Immunohistofluorescence displaying localization of SDCCAG8 (green) and acetylated α-tubulin (red) marking the CC or γ-tubulin (purple) marking the basal body of the photoreceptor sensory cilium in WT and Spata7 mutant retinae. (b) Retinal immunofluorescence displaying similar localization pattern in IFT52 and C21ORF2 (green) at basal body (as indicated by arrows) and RP1 at the axoneme in both WT and Spata7 mutant retinae. (c) Immunohistofluorescence displaying localization of AHI1, NPHP4, and RPGR shown in green in the CC of Sdccag8^mut mice retinae (P15). Bars, 5 µm.