Improved blood flow recovery in VASP^−/− mice after ischemia. WT (+/+) and VASP^−/− (−/−) mice underwent femoral artery excision, and blood flow recovery was assessed by laser Doppler imaging immediately before (day −1) and after ligation (days 0, 3, 7, 14, and 21). Bar, 5 mm. (A) Representative laser Doppler images. (B) Time course of the recovery of blood flow as the ratio of the ligated to nonligated hindlimb; n = 10 animals per group; error bars, SEM; *, P < 0.05; **, P < 0.01 (two-way ANOVA/Bonferroni).