Model for kinetochore and AIR-2/Aurora B–mediated anaphase regulation. Model depicting DNA (blue), microtubules (green), the ring complexes with AIR-2 (orange), AIR-2 (yellow), the ring complexes without AIR-2 (red), and kinetochores (purple). In normal meiosis (left), kinetochores are removed from chromosomes, AIR-2 relocalizes to the microtubules, and the ring complexes begin to disassemble by mid anaphase. Under many types of perturbations (a congression defect is depicted on the right), AIR-2 remains with the rings throughout mid anaphase, keeping the microtubule channels open. Chromosomes continue segregating, despite retention of kinetochores on chromosomes. By late anaphase, AIR-2 relocalizes to the microtubules and cytokinesis occurs.