Figure 6.
Figure 6. A STRIPAK complex prevents autophagic vesicle accumulation. (A) Quantification of autophagic vesicle (AV) accumulation in terminal boutons of NMJ4 when core STRIPAK components (Mob4, Strip, and Ccm3) were depleted in motoneurons. (B) BFP-CKA and Ch-Mob4 cotransport in axons. Arrowheads indicate punctae that are cotransporting. Bars, 10 µm. (C) Quantification of autophagic vesicle accumulation after expression of hpo, hpoT195E, depletion of CKA alone, depletion of Hpo alone, or simultaneous depletion of Hpo and CKA. n, number of terminal boutons scored. Berger’s unconditional exact test results: *, P < 0.05; **, P < 0.005; ns, not significant.

A STRIPAK complex prevents autophagic vesicle accumulation. (A) Quantification of autophagic vesicle (AV) accumulation in terminal boutons of NMJ4 when core STRIPAK components (Mob4, Strip, and Ccm3) were depleted in motoneurons. (B) BFP-CKA and Ch-Mob4 cotransport in axons. Arrowheads indicate punctae that are cotransporting. Bars, 10 µm. (C) Quantification of autophagic vesicle accumulation after expression of hpo, hpoT195E, depletion of CKA alone, depletion of Hpo alone, or simultaneous depletion of Hpo and CKA. n, number of terminal boutons scored. Berger’s unconditional exact test results: *, P < 0.05; **, P < 0.005; ns, not significant.

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