Figure 2.
Figure 2. Ultrastructure of axonal lysosome accumulations in JIP3 KO neurons. (A and B) Low-magnification EM images of WT and JIP3 KO neurons showing increased abundance of axonal lysosomes in JIP3 KO neurons (arrows). Bars, 5 µm. (C) Higher-magnification image of one such JIP3 KO axonal swelling (arrow) reveals the selective accumulation of organelles with lysosome-like morphology. Bar, 1 µm.

Ultrastructure of axonal lysosome accumulations in JIP3 KO neurons. (A and B) Low-magnification EM images of WT and JIP3 KO neurons showing increased abundance of axonal lysosomes in JIP3 KO neurons (arrows). Bars, 5 µm. (C) Higher-magnification image of one such JIP3 KO axonal swelling (arrow) reveals the selective accumulation of organelles with lysosome-like morphology. Bar, 1 µm.

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