Figure 5.

Two simple models of a KT as a viscoelastic object consisting of a spring and a dashpot. (A and B) Schematic representation of the models. A spring of a stiffness κ and a dashpot of a viscous drag coefficient γ are connected in series (A) or in parallel (B). The KT (pink ellipse) is under tension F and has a length x. In A, the length is the sum of the length of the spring, xs, and the length of the dashpot, xd. The equations of the models are given under the schemes. (C and D) KT length as a function of time for the models in A and B, respectively, for a constant tension F that starts to act at time t = 0 and stops at t = T1. The length of a control KT is denoted xc. (E and F) Relaxed length as a function of the stretched length (dark green) for the models in A and B, respectively. In E, γ = 5 × 105 pNs/µm, κ = 1,000 pN/µm, and xc = 0.7 µm, whereas F and t were varied simultaneously in the intervals F = 400–1,000 pN and T1 = 7–12 min, as shown in the inset. In F, κ = 100 pN/µm, xc = 0.4 µm, and F was varied in the interval 50–200 pN. Horizontal and oblique dashed lines correspond to complete relaxation to the control length xc and no relaxation, respectively.

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