Figure 5.

Mffgt and dm phenotypes in liver, testis, and cerebellum. (A) Comparison of liver to body mass ratio (n ≥ 10). (B) ALT levels in serum (n = 5–13). (C and E) Testis to body mass ratio in Mffgt and dm (C; n ≥ 5) and Stra8-Cre lines (E; n ≥ 6). (D and F) Hematoxylin and eosin stain of testicular cross sections in 8–9-wk-old Mffgt and dm (D) and Stra8-Cre lines (F). Note that only control and Mffgt sections contain spermatozoa (arrows). (G) Anticalbindin immunofluorescence illuminating cerebellar PC. Error bars = SEM. P-values as compared with the wild type: ^, P ≤ 0.05; *, P ≤ 0.01; **, P ≤ 0.001. Bars, 50 µm. WT, wild type.

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