Figure 8.
Figure 8. The actin-bundling activity of AnxA2 modulates the formation of the initial fusion pore. (A) Schema showing the parameters of the PSF signal measured in B, C, and D panels. NT, nontransfected cells; A2-WT, cells transfected with AnxA2-GFP WT; A2-K286A, cells transfected with AnxA2-K286A-GFP; NT + WA, cells treated for 1 h with 5 µM WA. Data are expressed as mean ± SEM (error bars). *, P < 0.05; **, P < 0.01.

The actin-bundling activity of AnxA2 modulates the formation of the initial fusion pore. (A) Schema showing the parameters of the PSF signal measured in B, C, and D panels. NT, nontransfected cells; A2-WT, cells transfected with AnxA2-GFP WT; A2-K286A, cells transfected with AnxA2-K286A-GFP; NT + WA, cells treated for 1 h with 5 µM WA. Data are expressed as mean ± SEM (error bars). *, P < 0.05; **, P < 0.01.

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