Figure 4.
Expression of α6 integrin is associated with both locomotive and proliferative capacities. (A) Serial images of a progressive growing colony were collected for 60 min, and then the colony was immediately fixed and stained with an antibody against α6 integrin (17D11). Bars, 50 µm. (B) Magnification of the area outlined by the red boxes in A. The colors in the left column indicate the locomotion speed (µm/h) of each cell in the colony. Bars, 20 µm. (C) Colony-forming efficiency of α6high and α6low keratinocyte population after serial cultivation. For more detail, see Fig. S3 F. Bar, 10 mm.