SOL-neuron material transfer in the adult mouse brain. (A) Reporter-positive neurons (arrowheads) in the hippocampal DG and CA2, septum, and amygdala of Sox10-iCreER^T2:Sun1-sfGFP mice at 4 d after TAM. (B) Rpl10a-EGFP⁺ neurons (arrowheads) in the cortex of Sox10-iCreER^T2:Rpl10a-EGFP mice at 24 h and 5 d after saline or LPS injection. (C) Quantification of Rpl10a-EGFP⁺ neurons in the cortex at 24 h and 5 d after LPS. (D) SOL-neuron nuclear pair immunoreactive for ribosomal Rpl10a-EGFP and histone H2B-mCherry in the cortex of adult Sox10-Cre:Rpl10a-EGFP H2B-mCherry mouse. Note, dense DAPI-labeled nuclei of SOL and diffuse DAPI-labeled neuronal nucleus. (E and F) TEM images of SOL-neuron pair with intact plasma membrane (PM) between nuclei. Multiple myelinated axons (a) are positioned close to SOL-neuron pair. All data are presented as mean ± SEM. Each circle represents an individual animal. P value was determined by one-way ANOVA with Bonferroni post hoc test. ns, P > 0.05. Data are representative of two (D), three (A–C), and four (E and F) independent experiments. Scale bar: 100 µm for DG in A and 20 µm for its enlargement; 50 µm for CA2, amygdala, and septum in A and for B; 10 µm for D and 5 µm for enlargement in D; 2 µm for E; and 1 µm for F. CA, cornu ammonis; Cx, cortex; LV, lateral ventricle; N, neuron; ns, not significant; SVZ, subventricular zone.