Figure S5.

Overlap and GO term enrichment of genes with CCR2 + CX3CR1 + DP monocytes of the nephritic kidney and genes reported in tumor-associated monocytes. (A) Heatmap of cluster markers overexpressed in kidney DP cells (Kid DP) in comparison to spleen DP (Spl DP) cells plotted across clusters of Wt/KO Med, Ccr2 KO:EC, and Wt:EC. (B) GSEA-GO-Bp for those markers of Wt monocytes cultured on endothelium which were overexpressed in kidney in comparison to spleen DPs (Kid DP > Spl DP). OR, odds ratio. (C) GSEA-GO-Bp for those markers of Wt monocytes cultured with activated endothelial cells, which had higher expression in mMono3 than mMono1, mMono2, and mMonoDC populations identified in Zilionis et al. (2019).

or Create an Account

Close Modal
Close Modal