POTCs were predominantly ablated by Vegfr2 deletion. (A and B) UMAP plots for reclustered EC1 and EC2 cells in Fig. 7 B. Types of ECs are assigned based on known markers for arterial endothelial cells (AECs), venous endothelial cells (VECs), capillary endothelial cells (Capil1, 2), and POTCs. (C) UMAP plots for reclustered EC1 and EC2 cells and cell counts (%) for each cluster. Red color indicates FC >2.5. (D) Heatmaps showing expression levels of endothelial tip cell marker genes. (E) Top 13 upregulated genes in POTCs (vs. all EC clusters or vs. Capil1). Red color indicates gene markers for tip cells and VEGF receptors.