Odontoblast Vegfr2 was dispensable for tooth formation. (A) Bright-field view of mandibles. Molar extrusion was intact in Osx–Cre^ERT2+Vegfr2^flox/flox mice. (B–I) Section specimens at P12 and quantification (H, control [Cont] n = 6, Osx–Cre^ERT2+Vegfr2^flox/floxn = 6; I, Cont n = 3, Osx–Cre^ERT2+Vegfr2^flox/floxn = 3). Osx–Cre^ERT2+Vegfr2^flox/flox mice exhibited no apparent blood vessel or odontoblast defects. Scale bars: 500 µm (A); 200 µm (B and C); 50 µm (D–G). Data are presented as means ± SD. Comparisons between two groups were evaluated using a two-sided Student’s t test.