Relationship between age or sex and and NP CXCL10 in 140 SARS-CoV-2–positive patients. Related to Fig 2. (A) Age distribution of 140 patients studied. (B) Sex distribution of 140 patients studied. (B) Sex distribution and inpatient/outpatient status of 140 patients studied. (C) Comparison of age in outpatients versus admitted patients. Number of patients shown in parentheses. Groups were compared by unpaired t test, with P value shown. (D) Correlation analysis showing lack of significant correlation between age and NP CXCL10 protein level, based on 140 patients. (E and F) Comparison of NP CXCL10 protein level (E) and viral load (F) based on age and inpatient/outpatient status. No significant differences were detected between groups by unpaired t test. (G and H) Correlation between viral load and NP CXCL10 in all patients (G) and outpatients (H) in all patients or patients segregated by sex. For all patients, according to simple linear regression analysis, the slope of all samples is significantly nonzero (r² = 0.2030, P < 0.0001), but slopes are not significantly different for each sex. For outpatients only, the slope of the regression line is not significantly nonzero, likely due to lower numbers (male [M] outpatient, n = 18; female [F] outpatient, n = 20).