Relationship between NP CXCL10 and viral load in 140 SARS-CoV-2–positive patients. Related to Fig. S2. (A) NP CXCL10 level in patients testing positive for SARS-CoV-2 by RT-qPCR at Yale New Haven Hospital in March 2020. Black symbols indicate patients tested as outpatients or in the emergency department and not admitted to the hospital, and red symbols indicate patients admitted to the hospital. (B) Ct value for SARS-CoV-2 N1 gene in outpatients and admitted patients. Number in parentheses (A and B) indicates the number of outpatient (total n = 38) and admitted (total n = 102) samples for which data were available. Difference between groups was evaluated using an unpaired Student’s t test, with P values shown. (C) Regression analysis showing relationship between viral load and NP CXCL10 protein for all samples (black solid line, r² and P value indicated) or only outpatients (dashed black line) or admitted patients (dotted red line). (D) Days of symptoms reported before testing for samples with this information available (number indicated in parentheses). Difference was not significant by a Student’s t test.