Figure 5.
Figure 5. Placental edema, HF, and fetal demise in mice lacking Calcrl. (A) Placenta from E13.5 Calcrl+/+ and edematous Calcrl−/− littermates, revealing significant interstitial edema within an expanded junctional zone (jz). Yellow arrows highlight fluid filled spaces in the jz. (B) Representative images of E17.5 Calcrlfl/fl and Calcrlfl/fl/Lyve1-Cre littermates. Asterisks indicate edema. n = 5–7 animals in each group. (C) Representative images of E14.5 Calcrlfl/fl and Calcrlfl/fl; Prox1-CreERT2 littermates from tamoxifen treated dams. Asterisks indicate edema. n = 8–10 animals in each group. Bars, 2 mm.

Placental edema, HF, and fetal demise in mice lacking Calcrl. (A) Placenta from E13.5 Calcrl+/+ and edematous Calcrl−/− littermates, revealing significant interstitial edema within an expanded junctional zone (jz). Yellow arrows highlight fluid filled spaces in the jz. (B) Representative images of E17.5 Calcrlfl/fl and Calcrlfl/fl/Lyve1-Cre littermates. Asterisks indicate edema. n = 5–7 animals in each group. (C) Representative images of E14.5 Calcrlfl/fl and Calcrlfl/fl; Prox1-CreERT2 littermates from tamoxifen treated dams. Asterisks indicate edema. n = 8–10 animals in each group. Bars, 2 mm.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal