A radioprotective shield reduces the recruitment of BMDMCs to the liver vasculature. (A) Experimental outline of PHx-induced liver regeneration in irradiation-conditioned GFP⁺ bone marrow–transplanted mice in the absence or presence of a liver shield. (B) Mice were irradiated with or without liver shield. Representative images of liver sections of bone marrow chimeric mice costained with GFP, CD45, and CD31 (EC-specific surface marker). Zoomed-in images are shown at the bottom. Arrows indicate GFP⁺ ECs. Arrowheads indicate GFP⁺ hematopoietic cells in the shielded liver. Scale bars, 50 µm. (C) The percentage of GFP⁺ ECs in livers of mice irradiated in the presence or absence of a liver shield was analyzed by FACS (mean ± SD, n = 6 mice). ***, P < 0.001 (two-tailed Student’s t test).