Figure 2.

Thymus receptivity correlates with numbers of ETP and DN2 thymocytes. (A) Analysis of WT, CCR7−/−, CCR9−/−, and DKO thymi 21 d after transfer of congenic (CD45.1 and CD45.1/2) WT lin BM precursors. Representative plots of two independent experiments, n = 6–8 for each genotype. (B) Correlation between abundance of recipient thymocyte populations and thymus receptivity, depicted as percentage of engraftment. Recipient mice were 4–11 wk old. Donor mice were 7–8 wk old. Each data point represents an average of six to eight mice/genotype from two independent experiments. R2 = coefficient of correlation.

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